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tecovirimat will enhance the level or result of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Use Caution/Observe. Tecovirimat is a weak inhibitor of CYP2C8 and CYP2C19. Watch for adverse consequences if coadministered with delicate substrates of these enzymes.diazepam will improve the level or outcome of isavuconazonium sulfate by affec